KPV 10mg
Also known as Lys-Pro-Val, alpha-MSH 11-13, α-MSH fragment
KPV is the C-terminal tripeptide (Lys-Pro-Val) of alpha-melanocyte-stimulating hormone (α-MSH).
£24.99
£2.50/mg
Available to order
Same-day dispatch on working days before 2pm
Spend £150 for 10% off, £250 for 15%, £400 for 20%. Applied automatically in your basket.
Need a diluent?
Bacteriostatic water 10ml, £5.99
RESEARCH OVERVIEW
What is KPV?
KPV corresponds to residues 11 to 13 of α-MSH. In experimental systems it retains much of the anti-inflammatory activity attributed to the parent hormone, without the pigmentary effects associated with melanocortin-1 receptor activation.
Studies have examined its uptake through the PepT1 transporter in intestinal epithelial cells, its effects in models of intestinal inflammation, and delivery approaches such as hydrogels and transdermal systems.
Selected literature
- A KPV-binding double-network hydrogel restores gut mucosal barrier in an inflamed colon Zhao Y et al. Acta Biomater, 2022. PMID 35245681
- Transdermal Iontophoretic Delivery of Lysine-Proline-Valine (KPV) Peptide Across Microporated Human Skin Pawar K et al. J Pharm Sci, 2017. PMID 28343991
- PepT1-mediated tripeptide KPV uptake reduces intestinal inflammation Dalmasso G et al. Gastroenterology, 2008. PMID 18061177
KPV research applications
Areas explored in published in-vitro and animal-model research. No clinical claims are made.
- Intestinal inflammation models
- PepT1 transporter uptake studies
- Cytokine signalling in epithelial cells
- Drug delivery formulation research
KPV vs BPC-157
BPC-157 is also studied in gastrointestinal models, but it is a 15-amino-acid gastric peptide rather than an α-MSH fragment.
View BPC-157Specifications
| Product | KPV |
|---|---|
| Also known as | Lys-Pro-Val, alpha-MSH 11-13, α-MSH fragment |
| Quantity per vial | 10mg |
| CAS number | 67727-97-3 |
| Molecular formula | C16H30N4O4 |
| Molecular weight | 342.4 g/mol |
| Sequence | Lys-Pro-Val |
| Form | Lyophilised powder |
| Appearance | White lyophilised powder |
| Purity | Each batch tested by HPLC and MS; certificate on release |
| Storage | -20°C long term, dry and protected from light |
| Classification | For laboratory research use only |
Purity and testing
Every batch is sent to an independent laboratory for identity and purity analysis by high-performance liquid chromatography (HPLC) and mass spectrometry (MS). Certificates are published on our Lab Reports page as each batch is released, and the batch number on your vial matches its certificate.
Want the report for a specific batch before ordering? Contact us and we will send it.
Laboratory handling
Reconstitution
- Allow the sealed vial to reach room temperature.
- Wipe the stopper with an alcohol swab.
- Add diluent slowly down the inside wall of the vial.
- Swirl gently until dissolved. Do not shake.
- Label with concentration and date, then refrigerate.
Storage
- Lyophilised: -20°C for long-term storage, sealed and dry, away from light.
- Short term: 2 to 8°C for weeks in the sealed vial.
- Reconstituted: 2 to 8°C, protected from light. Avoid repeated freeze-thaw cycles.
KPV FAQs
Is KPV for human use?+
No. KPV is sold strictly for laboratory research use only. It is not a medicine, food supplement or cosmetic and must not be used in humans or animals.
How is KPV tested?+
Each batch is tested for identity and purity by an independent laboratory using HPLC and mass spectrometry. Certificates are published on our Lab Reports page as each batch is released, and you can request the report for your batch at any time.
How should KPV be stored?+
Lyophilised material should be stored sealed, dry and protected from light, ideally at -20°C for long-term storage. After reconstitution, laboratories typically store solutions at 2 to 8°C and avoid repeated freeze-thaw cycles.
How quickly will my KPV order arrive?+
Orders placed before 2pm on a working day are dispatched the same day by Royal Mail Tracked 24. Delivery is free over £50, otherwise £4.99.
Do I need bacteriostatic water for KPV?+
Lyophilised peptides are supplied as dry powder. Laboratories reconstitute them with a suitable diluent such as bacteriostatic water, which we stock separately. Our reconstitution calculator works out the resulting concentration.
REGENERATIVE RESEARCH
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KPV 10mg
£24.99 £2.50/mg