LL-37 5mg
Also known as cathelicidin, hCAP18, CAMP
LL-37 is the only human cathelicidin antimicrobial peptide, a 37-amino-acid cationic peptide cleaved from hCAP18.
£29.99
£6.00/mg
Available to order
Same-day dispatch on working days before 2pm
Spend £150 for 10% off, £250 for 15%, £400 for 20%. Applied automatically in your basket.
Need a diluent?
Bacteriostatic water 10ml, £5.99
RESEARCH OVERVIEW
What is LL-37?
LL-37 is released from its precursor protein hCAP18 and forms an amphipathic alpha-helix that interacts with microbial membranes. Beyond direct antimicrobial activity it has immunomodulatory roles, including effects on chemotaxis, neutrophil extracellular trap formation and epithelial repair.
Its expression is regulated by vitamin D signalling, which has made it a frequent subject of innate immunity research.
Selected literature
- Vitamin D triggers hCAP18/LL-37 production: Implications for LL-37-induced human osteoblast cytotoxicity Aidoukovitch A et al. Biochem Biophys Res Commun, 2024. PMID 38642493
- LL-37, a Multi-Faceted Amphipathic Peptide Involved in NETosis Radic M et al. Cells, 2022. PMID 35954305
- LL-37: A Direct Link Between Inflammation and Myocardial Infarction Schneider DJ et al. JACC Basic Transl Sci, 2024. PMID 39170953
LL-37 research applications
Areas explored in published in-vitro and animal-model research. No clinical claims are made.
- Antimicrobial membrane interaction assays
- Innate immune signalling and chemotaxis
- Neutrophil extracellular trap (NET) research
- Wound and epithelial repair models
LL-37 vs KPV
KPV is studied mainly for anti-inflammatory signalling, whereas LL-37 is primarily studied as an antimicrobial and immunomodulatory peptide.
View KPVSpecifications
| Product | LL-37 |
|---|---|
| Also known as | cathelicidin, hCAP18, CAMP |
| Quantity per vial | 5mg |
| CAS number | 154947-66-7 |
| Molecular formula | C205H340N60O53 |
| Molecular weight | 4,493.0 g/mol |
| Form | Lyophilised powder |
| Appearance | White lyophilised powder |
| Purity | Each batch tested by HPLC and MS; certificate on release |
| Storage | -20°C long term, dry and protected from light |
| Classification | For laboratory research use only |
Purity and testing
Every batch is sent to an independent laboratory for identity and purity analysis by high-performance liquid chromatography (HPLC) and mass spectrometry (MS). Certificates are published on our Lab Reports page as each batch is released, and the batch number on your vial matches its certificate.
Want the report for a specific batch before ordering? Contact us and we will send it.
Laboratory handling
Reconstitution
- Allow the sealed vial to reach room temperature.
- Wipe the stopper with an alcohol swab.
- Add diluent slowly down the inside wall of the vial.
- Swirl gently until dissolved. Do not shake.
- Label with concentration and date, then refrigerate.
Storage
- Lyophilised: -20°C for long-term storage, sealed and dry, away from light.
- Short term: 2 to 8°C for weeks in the sealed vial.
- Reconstituted: 2 to 8°C, protected from light. Avoid repeated freeze-thaw cycles.
LL-37 FAQs
Is LL-37 for human use?+
No. LL-37 is sold strictly for laboratory research use only. It is not a medicine, food supplement or cosmetic and must not be used in humans or animals.
How is LL-37 tested?+
Each batch is tested for identity and purity by an independent laboratory using HPLC and mass spectrometry. Certificates are published on our Lab Reports page as each batch is released, and you can request the report for your batch at any time.
How should LL-37 be stored?+
Lyophilised material should be stored sealed, dry and protected from light, ideally at -20°C for long-term storage. After reconstitution, laboratories typically store solutions at 2 to 8°C and avoid repeated freeze-thaw cycles.
How quickly will my LL-37 order arrive?+
Orders placed before 2pm on a working day are dispatched the same day by Royal Mail Tracked 24. Delivery is free over £50, otherwise £4.99.
Do I need bacteriostatic water for LL-37?+
Lyophilised peptides are supplied as dry powder. Laboratories reconstitute them with a suitable diluent such as bacteriostatic water, which we stock separately. Our reconstitution calculator works out the resulting concentration.
REGENERATIVE RESEARCH
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LL-37 5mg
£29.99 £6.00/mg