Semaglutide 5mg
Also known as GLP-1, sema, GLP-1 analogue
Semaglutide is a long-acting GLP-1 receptor agonist peptide with 94% sequence homology to native human GLP-1.
£19.99
£4.00/mg
Strength
Available to order
Same-day dispatch on working days before 2pm
Spend £150 for 10% off, £250 for 15%, £400 for 20%. Applied automatically in your basket.
Need a diluent?
Bacteriostatic water 10ml, £5.99
RESEARCH OVERVIEW
What is Semaglutide?
Semaglutide is a GLP-1 analogue with two amino acid substitutions (Aib at position 8 and Arg at position 34) and a C18 fatty diacid attached through a linker at lysine 26. These modifications protect it from DPP-4 degradation and promote albumin binding, giving it a long half-life.
It is among the most studied peptides in metabolic research, with an extensive literature on GLP-1 receptor signalling, appetite regulation and glucose homeostasis. It is widely used as the benchmark GLP-1 receptor agonist in comparative work.
Selected literature
- Subcutaneously administered tirzepatide vs semaglutide for adults with type 2 diabetes: a systematic review and network meta-analysis of randomised controlled trials Karagiannis T et al. Diabetologia, 2024. PMID 38613667
- Clinical Pharmacokinetics of Semaglutide: A Systematic Review Yang XD et al. Drug Des Devel Ther, 2024. PMID 38952487
Semaglutide research applications
Areas explored in published in-vitro and animal-model research. No clinical claims are made.
- GLP-1 receptor signalling and desensitisation studies
- Glucose-stimulated insulin secretion assays
- Central appetite regulation research in animal models
- Benchmark comparator in incretin pharmacology
Semaglutide vs Tirzepatide
Tirzepatide acts at the GIP and GLP-1 receptors, whereas semaglutide is selective for the GLP-1 receptor.
View TirzepatideSpecifications
| Product | Semaglutide |
|---|---|
| Also known as | GLP-1, sema, GLP-1 analogue |
| Quantity per vial | 5mg |
| CAS number | 910463-68-2 |
| Molecular formula | C187H291N45O59 |
| Molecular weight | 4,114.0 g/mol |
| Form | Lyophilised powder |
| Appearance | White lyophilised powder |
| Purity | Each batch tested by HPLC and MS; certificate on release |
| Storage | -20°C long term, dry and protected from light |
| Classification | For laboratory research use only |
Purity and testing
Every batch is sent to an independent laboratory for identity and purity analysis by high-performance liquid chromatography (HPLC) and mass spectrometry (MS). Certificates are published on our Lab Reports page as each batch is released, and the batch number on your vial matches its certificate.
Want the report for a specific batch before ordering? Contact us and we will send it.
Laboratory handling
Reconstitution
- Allow the sealed vial to reach room temperature.
- Wipe the stopper with an alcohol swab.
- Add diluent slowly down the inside wall of the vial.
- Swirl gently until dissolved. Do not shake.
- Label with concentration and date, then refrigerate.
Storage
- Lyophilised: -20°C for long-term storage, sealed and dry, away from light.
- Short term: 2 to 8°C for weeks in the sealed vial.
- Reconstituted: 2 to 8°C, protected from light. Avoid repeated freeze-thaw cycles.
Semaglutide FAQs
Is Semaglutide for human use?+
No. Semaglutide is sold strictly for laboratory research use only. It is not a medicine, food supplement or cosmetic and must not be used in humans or animals.
How is Semaglutide tested?+
Each batch is tested for identity and purity by an independent laboratory using HPLC and mass spectrometry. Certificates are published on our Lab Reports page as each batch is released, and you can request the report for your batch at any time.
How should Semaglutide be stored?+
Lyophilised material should be stored sealed, dry and protected from light, ideally at -20°C for long-term storage. After reconstitution, laboratories typically store solutions at 2 to 8°C and avoid repeated freeze-thaw cycles.
How quickly will my Semaglutide order arrive?+
Orders placed before 2pm on a working day are dispatched the same day by Royal Mail Tracked 24. Delivery is free over £50, otherwise £4.99.
Which Semaglutide strengths are available?+
Semaglutide is available in 5mg (£19.99), 10mg (£34.99). Larger vials cost less per mg.
Do I need bacteriostatic water for Semaglutide?+
Lyophilised peptides are supplied as dry powder. Laboratories reconstitute them with a suitable diluent such as bacteriostatic water, which we stock separately. Our reconstitution calculator works out the resulting concentration.
METABOLIC RESEARCH
Related research compounds
Researcher reviews
Reviews come from signed-in customers and are moderated before publication.
No reviews yet. Bought this compound? Share your experience below.
Semaglutide 5mg
£19.99 £4.00/mg